Oral Antibody Treatment In The Works To Fight Gut And Inflammatory Diseases
Scientists have made a major breakthrough in the gut health realm. Previously, treatment for gastrointestinal and inflammatory diseases wasn’t feasible through oral administration. New developments now combine the convenience of oral medication with the advantages of antibody therapies. This comes as a big relief to sufferers of inflammatory diseases such as ulcerative colitis and Crohn’s, as well as gut and digestive problems.
For animals and humans who suffer from these conditions, treatments previously included antibiotics, steroids, supplements, and antibody injections. The medication formulated recently could eliminate the need for some of these treatments and sufferers may be able to quickly add it to their food without the need for painful shots at the doctor’s office.
What Are Gut And Inflammatory Diseases?
Common gut and inflammatory diseases include reflux, lactose intolerance, inflammatory bowel disease, ulcerative colitis and Crohn’s. People suffering from these conditions often experience bloating, diarrhea, cramps, and stomach pains. With certain treatments and lifestyle changes, symptoms can be managed but many never feel complete relief.
Reflux, heartburn, and GERD are among the most common digestive problems. The hot or burning sensation coming up your throat is never a welcome feeling. While most of us have encountered this at one point or another, chronic sufferers can be in serious pain and suffer from more complicated medical conditions later in life such as reflux disease or esophageal cancer.
Lactose intolerance is another common gut ailment. People with this condition lack the enzyme we need to digest the sugars found in milk. Anywhere from thirty minutes to two hours after eating a dairy product, people will feel gas pains, nausea, diarrhea, or cramping. Using a breath, blood or stool test, doctors can easily diagnose this condition.
Inflammatory bowel diseases such as Crohn’s or ulcerative colitis are more serious gut and inflammatory diseases. Symptoms include diarrhea, pain in the abdomen, anemia, weight loss, and rectal bleeding in some cases. These can often be misdiagnosed as irritable bowel syndrome, ulcers, infections or appendicitis. With both diseases, your body will attack the gastrointestinal tract and immune system error. Treatments include steroids, immunosuppressants, and prescription anti-inflammatory medications. Combinations of these may prove effective in avoiding surgery and keeping pain under control.
Due to their inability to reach the necessary gastrointestinal tissues, oral antibodies haven’t been able to survive digestion. Previously, treatment included antibodies being injected into the bloodstream. This prevented infectious diseases, inflammation, and cancer. This method was the most common since antibody treatments weren’t previously designed for ingestion. Until now, the hostile environment oral remedies met along the way to the gut made it impossible for any treatment to be effective.
The New Oral Treatments
Luckily for people with digestive and gut health issues, relief may be on the way. If polled, most people would likely prefer an oral medication taken at home over needles and injections at a doctors office any day.
Scientists at VIB-UGent tested the technology on piglets who are highly prone to getting an infection that causes diarrhea. Currently, pigs are treated with antibiotics for this ailment but it can cause complications with long-term use such as antibiotic resistance. The piglets that were given the treatment in their feed were protected against the infection.
Since guts in humans and pigs are scientifically similar, these findings could mean big things for people with gut and inflammatory issues. We can soon use food-processing methods using yeast cells, and soybean seeds to produce the needed antibodies for treatment. The medication comes in a powder form that can be manufactured quickly. You can ingest the powder by adding it to your food without the need for any encapsulation. This breakthrough can make a tremendous difference to both humans and animals alike who suffer from these conditions. We can soon see these powders as additives to foods, feeds, and biopharmaceuticals.